比特诺尔的动物药效学研究  

STUDY ON PHARMACODYNAMIC OF BITNAL

作　　者：周尔凤[1] 于学敏 龙平[1] 顿文[1] 闫超华[1] 王振南 李鸿茂 赵毅 冯少波 周萍 赵卫建 魏宝华 

机构地区：[1]山西医学院药理教研室,太原030001 [2]山西大同药物研究所 [3]山西大同药品检验所

出　　处：《中国新药杂志》1996年第1期45-47,共3页Chinese Journal of New Drugs

摘　　要：观察了比特诺尔对动物溃疡性结肠炎、消化性溃疡和胃炎的作用。结果表明:比特诺尔对溃疡性结肠炎作用显著,柳氮磺胺吡啶(SASP)与对照组相比,差异非常显著(P<0.01),得乐组与对照组相比无显著差异(P>0.05),其溃疡总数抑制率分别为47.2%、49.2%、3.8%;比特诺尔和得乐抗胃炎、胃溃疡和十二指肠溃疡作用无显著差异(P>0.05),但二者和对照组相比均有显著和非常显著的差异(P<0.05或 P<0.01)。The pharmacodynamic of Bitnal in treatment of chronic ulcerative colitis, peptic ulcer,and gastritis was studied on animals.Results showed that Bitnal has a signifi- cant effect in treatment of ulcerative colitis in comparision with control and that its efficacy is as effective as those of SASP with a total ulcer depression rate of 47.2% for Bitnal,49.2% for SASP and 3.8% for control.There are no significant difference in efficacy between Bit- nal and Denol in treatment of above mentioned symptoms.

关 键 词：比特诺尔 溃疡性结肠炎 胃炎 胃溃疡 药理 

分 类 号：R975[医药卫生—药品]