终末器官对神经再生影响的实验研究  

Influence of end organs on peripheral regeneration :an experimental study

作　　者：陈振兵[1] 洪光祥[1] 王发斌[1] 黄省秋[1] 万圣祥[1] 黄启顺[1] 康皓[1] 

机构地区：[1]同济医科大学附属协和医院手外科,武汉430022

出　　处：《中华手外科杂志》1996年第1期41-43,共3页Chinese Journal of Hand Surgery

摘　　要：探讨神经远端终末器官对神经再生的影响。方法：采用硅胶管桥接大鼠双侧坐骨神经，一侧硅胶管套接的远端神经连有终末器官，另一侧远端神经不连有终末器官。术后２、４、６周取标本，通过肉眼观察、光镜、电镜和轴突图象分析仪观察神经再生情况。结果：从各时间段的标本检测，在再生神经干直径，有髓纤维的密度、数目，远端神经的面积及形态学比较，两者均无显著差异。结论：远端神经连有终末器官与否虽不是影响神经能否再生的关键因素。The sciatic nerves of adult rats were transected and the cut ends of the transected nerves were placed in silicone tubers. On one side the distal nerve was connected with the end organs and on the contralateral side not connected with the end organs. After 2 .4.6 weeks, the rais were killed and the chambers together with adjacent nerve segments were removed for macroscopic, histologic and morphometric analysis. The results showed that the presence of the end organs influenced eventual maturation of nerve regeneration and the end organs were not essential to successful regeneration.

关 键 词：神经再生 终末器官 硅胶管 实验 

分 类 号：R651.3[医药卫生—外科学]