周围神经卡压松解的实验研究  

Experimental study on neurolysis

作　　者：虞聪[1] 胡必寺[1] 沈丽英[1] 顾玉东[1] 

机构地区：[1]上海医科大学华山医院手外科研究所,200040

出　　处：《中华手外科杂志》1996年第1期50-52,共3页Chinese Journal of Hand Surgery

摘　　要：周围神经卡压是常见病，多以手术松解来治疗。但各术式的优劣尚未见临床或实验报告。为解决此问题，进行了实验研究。方法：在Ｍａｃｋｉｎｎｏｎ［１，３］所设计的大鼠坐骨神经卡压模型的基础上，研究了神经卡压松解四种不同方法的优劣。实验分组，Ａ组，仅去除卡压：Ｂ组，去除卡压后用手术刀切开神经外膜；Ｃ组，去除卡压后，神经外膜内注射确炎舒松－Ａ：Ｄ组，去除卡压后再用手术刀切开神经外膜，然后在神经周围置确炎舒松－Ａ。术后不同时间（１～４周）进行电生理、组织学检测。结果：神经卡压物去除后，神经外膜内注射确炎舒松－Ａ，或切开神经外膜，周围再置确炎舒松－Ａ，这两种方法为较理想的神经卡压松解术式。Peripheral nerve compression is treated hy several methods of neurolysis. but it is not deter- mined which technique is superior . Four methods were compared experimentally on rats sciatic nerve models designed by Mackinnon[[1,3] . The rats were divided into 4 groups in group A only decompression wasper- fnrmed , in group B external neurolysis was done after decompression, in group C Injectio Triamcinoloni Ace- tonidi Acetatis ( TAtA) was placed topically after external neurolysis. The results were evaluated by electro- physiological and histological methods. It was concluded that TAA sub-epineurium injection after decompres- sion or tropical use after cxternal neurolysis were better in the releasing of nerve compression .

关 键 词：神经卡压松解 确炎舒松-A 周围神经 

分 类 号：R651.3[医药卫生—外科学]