4种药物防治高原脱适应的对比观察  

The Contrastive Observation of Four Kinds of Medicine Prevention and treatment De-adaptation to High altitude

作　　者：王宏运[1] 张西洲[1] 李彬[1] 崔建华[1] 哈振德[1] 马广全[1] 秦必文[1] 高亮[1] 

机构地区：[1]新疆叶城解放军第18医院,844900

出　　处：《高原医学杂志》2006年第1期26-28,共3页Journal of High Altitude Medicine

基　　金：兰州军区医药卫生科研基金资助项目(CXH-2005023)

摘　　要：目的筛选防治高原脱适应的药物品种。方法对驻守海拔5170m一年的57名某部官兵,在返回平原(海拔1400m)前5天随机分为5组,分别口服银杏叶片(12人)、复方红景天胶囊(12人)、刺五加片(11人)、复方党参胶囊(11人)、炒面胶囊(对照组,11人),至返回平原第7天停药,共服药12天。采用高原脱适应症状调查表调查部队返回平原第2天、4天、6天的高原脱适应情况,并计算出每天的总得分。采用二级定量负荷踏阶运动实验评价受试者返回平原第7天的PWC170和台阶指数。结果与对照组比较,复方党参组和复方红景天组高原脱适应症状显著减轻(P<0.01或P<0.05),且复方党参组明显优于银杏叶片组和刺五加组(P<0.05)。与对照组比较,复方党参组和复方红景天组PWC170和台阶指数均显著提高(P<0.05)。结论复方党参胶囊和复方红景天胶囊防治高原脱适应效果较好。Objective： Filtrate medicine of prevention and cure de--adaptation to high altitude. Methods： 57 youths defended at 5170m altitudes for one year were randomly divided into 5 groups before 5 days return plain （1 400m）. 12 persons in group 1 took orally gingkgo biloba, 12 persons in group 2 took rhodiola, 11 persons in group 3 took Ciwujiapian, 11 persons in group 4 took compound Dangshen and 12 persons in group 5 took placebo until arrived plain for 1 week. We investigated the symptom of de--adaptation to high altitude with de--adaptation questionary on the 2nd, 4th and 6th day, and counted the sum of score. We evaluated PWC170 and step index by heart rate during a given exercise experiment. Results： Compared with contrast group, the symptom of de--adaptation in compound Dangshen and rhodiola group reduced significantly （P〈0.01or P〈0.05）, and compound Dangshen is preceded than gingkgo biloba and Ciwujiapian（P〈0.05）. Compared with contrast group,the PWC170 and step index of compound Dangshen and rhodiola group increased significantly（P〈0.05） Conclusions. Compound Dangshen and rhodiola are better at prevention and cure de--adaptation to high altitude.

关 键 词：高海拔 高原脱适应 复方党参 复方红景天 工效实验 

分 类 号：R82[医药卫生—临床医学]