老年扩张型心肌病的临床研究  

The Clinical Study of Elder Dilated Cardiomyopathy

作　　者：吴振西[1] 王琼[1] 章仁品[1] 

机构地区：[1]中国人民解放军105医院,安徽合肥230031

出　　处：《医学综述》2006年第7期446-447,共2页Medical Recapitulate

摘　　要：目的研究老年人扩张型心肌病(DCM)的特征。方法通过临床观察对38例老年和78例非老年DCM患者的临床资料进行对比研究。结果①老年组室性心律失常发生率(60.5%)较非老年组(89.7%)低(P<0.05);②老年组低血钾、低血镁发生率高(分别为56.4%和29.6%),对洋地黄敏感性增加,易发生洋地黄中毒(28.9%);③老年组的病程(12.12±3.8)年和平均生存期(7.2±4.14)年均较非老年人[分别为(5.8±3.11)年和(3.8±2.4)年]长(均为P<0.05);④老年组的主要死因是充血性心力衰竭(80%)。结论老年人DCM的预后比非老年人相对较好,发病年龄越早,预后越差。心力衰竭,电解质失衡及交感神经兴奋是老年人DCM室性心律失常的主要原因。Objective To study the characteristics of elder dicated cadiomyopathy （DCM）. Methods The clinical data of dicated cardiomyopathy in 38 elder and 78 non-elder cases were comparatively studied through clinicol observations. Results ①The incidence of ventricular arrhythmia in the elder was lower that in the non-elder （00,5%vs89. 7 %, P 〈 0.05） ; ②The incidence of hypokalemia and hypomagnesiemia were higher in the elder （56.4 % and29.6% ）. The old patients were more to have digitalis intoxation because of their more sensitive to it （28.9%）;③Course of disease and mean survival period in the elder with DCMwas longer than those in the non-elder[ （ 12.12 ± 3.8）yrs and （7.2 ± 4.14 ）yrs vs（ 5.8 ± 3.11 ）yrs and （3.8 ± 2.4）yrs （all P 〈 0.05 ）] ;④The main cause of death was congestive heart failure in the elderly with DCM（80% ）. Conclusion The prognosis in the elder with DCM was better than that in the non-elder, the earlier the age of onset, the worse the prognosis. The main masons of ventrieular arrhythmia in the elder were heart failure, electrolyte inbalance and sympathetic excitation.

关 键 词：心肌病 充血性心力衰竭 心律失常 老年人 

分 类 号：R542.2[医药卫生—心血管疾病]