雪莲对正常的与辐射损伤的小鼠细胞免疫功能的影响  

Effect of saussurea medusa maxim on cellular immunity in normal and radiated damage mice

作　　者：王沛[1] 白丰沛[1] 

机构地区：[1]佳未斯医学院免疫学教研室,佳木斯154003

出　　处：《佳木斯医学院学报》1996年第2期8-9,共2页

摘　　要：雪莲是名贵中药,具有除寒、祛痰、强阳补血、调经和收缩子宫等功能。主治阳萎、经血不调、崩带、胎衣不下和风湿性关节炎等。对雪莲的免疫药理研究报道极少。本文就雪莲对小鼠细胞免疫功能的影响进行了实验研究。结果表明雪莲能增强小鼠脾细胞对ConA的增殖反应与混合淋巴细胞培养反应;对^(60)Co源照射所致上述两项指标的低下有明显地恢复作用,使辐射损伤引起的CD_4/CD_8比值倒置得以恢复正常。对小鼠DTH有抑制作用。故此,雪莲可能是一种有免疫调节作用的药物。The offecs of the saussurea medusa maxim(SMM) on cellular immunity in normal and radi- ated damage mice. The results showed that it markedly enhaced splenocyte response to conA pro- liferation and to mixed lymphocyte culture, that it markedly restored lowered functions due to radiation and that it inhibited DTH in mice. Those results suggest thst SMM may be an im- munomodulator.

关 键 词：雪莲 辐射损伤 细胞免疫 

分 类 号：R818.703[医药卫生—放射医学]