瘦素与胎儿生长发育的关系及研究进展  

Progress in Study on relationship between leptin and fetal growth and development

作　　者：成怡敏[1] 屈新中[1] 

机构地区：[1]西安交通大学医学院第一附属医院妇产科,陕西西安710061

出　　处：《中国妇幼健康研究》2006年第1期21-24,共4页Chinese Journal of Woman and Child Health Research

摘　　要：瘦素是新近发现的、脂肪组织合成分泌的激素,因其在实验动物饮食行为、能量代谢和生殖发育中起关键调节作用而日益受到关注。近年来研究发现瘦素不仅可调节体内的能量代谢和脂肪沉积,且与胎儿生长发育有着密切的关系。瘦素可调控胎儿体重的增长,在胎儿生长发育中起着重要的作用,成为近年来的研究热点之一。胎儿瘦素究竟来源于胎儿自身组织还是胎盘颇有争议。胎儿瘦素可受激素、性别、母亲因素、遗传因素等影响。该文将就瘦素与胎儿生长发育的关系及研究进展作以综述。Leptin is a recently found hormone produced by adipose tissue, it has attract particular attention because of its key regulatory action in dietary behavior, reproductive development and energy-metabolism of the experimental animals. Recently, it was found that leptin is closely related to fetal growth and development. Fetal leptin can regulate and control fetal body weight and plays an importnt role in fetal growth and development, so it becomes a hot - point of study in recent years. However, whether fetal leptin originates from fetal tissues themselves or placenta is controversial till now. The regulation of leptin synthesis and secretion depends on multiple factors such as hormone, sex, maternal factors, genetic factors and so on, In this review, we summarized progress in study on relationship of leptin with fetal growth and development.

关 键 词：瘦素 胎儿 生长发育 

分 类 号：R714.51[医药卫生—妇产科学]