低频交变磁场对肿瘤细胞作用的理论分析和实验结果  

Effects of Oscillating Magnetic Field on Cancer Cells: Theoretical Analysis and Experiments

作　　者：黄玲珍[1] 董良[2] 陈彦田[2] 齐瀚实[2] 肖登明[1] 

机构地区：[1]上海交通大学电气系,上海200030 [2]上海交通大学药学院,上海200030

出　　处：《现代生物医学进展》2006年第2期1-4,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(No.50477007)

摘　　要：本文研究了低频交变磁场对细胞作用的理论机理和实验结果。交变磁场和交变磁场感应的电场对运动离子产生电场力,加速离子的运行。基于该理论分析,设计了一系列的实验来验证假定的理论,实验采用两种肿瘤细胞系(HL-60 and SK-Hep-1)。将肿瘤细胞暴露于50Hz,20mT连续正弦磁场4天,每24小时检测上清液Na+和K+浓度。结果发现,照射组和对照组的Na+和K+浓度有显著变化,实验结果和理论分析相符。In this paper, a theoretical mechanism and experiments for the effects of low frequency oscillating magnetic field on cells were investigated and analysed. Magnetic field varying with time and its inducing electric field produce the force on the moving ions and accelerate the ions. On the basis of the theoretical analysis, a series of experiments were designed to test the supposed theory. Two human cancer cell lines （HL - 60 and SK- Hep- 1） were used in our experiment. The cancer cells were exposed to a continuous sinusoidal 50Hz, 20mT magnetic field for 4 days. Tne results demonstrate the significant changes of Na^＋ and K^＋ ion eoncentratious in cell supematant compared with the control group. These results of experiments appear to be consistent with the theoretical analysis.

关 键 词：磁场 感应电场 位移 肿瘤细胞 离子浓度 

分 类 号：Q279[生物学—细胞生物学] TE869[石油与天然气工程—油气储运工程]