血管造影图像序列中冠状动脉的三维运动估计  

Three-dimensional Motion Estimation of Coronary Artery from Single-plane Cineangiogram Sequences

作　　者：孙正[1] 郁道银[1] 黄家祥[1] 谢洪波[1] 陈晓冬[1] 

机构地区：[1]天津大学精密仪器与光电子工程学院光电信息技术科学教育部重点实验室(天津大学),天津300072

出　　处：《生物医学工程学杂志》2006年第2期428-432,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金项目(30500129);高等学校博士学科点专项科研基金项目(20030056018);中国博士后科学基金项目(2004036361)

摘　　要：提出了由两个角度的单面血管造影图像序列估计冠状动脉骨架树三维运动的算法。首先对冠状动脉造影图像序列进行二维预处理和二维运动估计。然后根据冠脉造影系统的透视投影模型得到两幅不同角度的造影图像之间的几何变换关系,以及空间点三维坐标的计算方法。最后,在对整个图像序列进行分析的过程中,将三维运动估计与重建结合起来,得到各骨架点的三维运动向量。采用临床得到的冠状动脉造影图像序列对算法进行了验证,并分析了误差源。This paper presents a method for estimating three-dimensional （3D） motion of coronary arteries from single-plane X-ray angiogram sequences on two views. Firstly, original images are preprocessed and twodimensional （2D） vessel skeletons are extracted. 2D motion estimation is performed along the skeletons in two images. Then geometrical transformation matrix between views is obtained based on perspective projection model for X-ray angiography system, and 3D coordinate of spatial points are calculated. The 3D motion estimation and reconstruction algorithm is applied along the two image sequences to accomplish 3D reconstruction of vessel skeletons and motion vectors between consecutive time instants. Its effectiveness has been demonstrated on clinical single-plane coronary artery angiograms and potential errors are discussed.

关 键 词：冠状动脉造影 三维运动估计 图像序列分析 

分 类 号：R310[医药卫生—基础医学]