某院临床标本细菌分布与耐药性分析  

Analysis of distribution of clinical bacterial isolates and antimicrobial resistance

作　　者：邱文影[1] 钟国权[1] 林学壬[1] 

机构地区：[1]清远市人民医院,广东清远511500

出　　处：《中国感染控制杂志》2006年第2期150-152,160,共4页Chinese Journal of Infection Control

摘　　要：目的了解某院各种临床标本的细菌分布及其对常用抗菌药物的耐药性。方法统计分析该院1998—2003年门诊及住院患者送检标本中分离并经鉴定的细菌及其耐药情况。结果6年共检出细菌4632株，其中革兰阴性（G^-）杆菌2759株（59．56％），革兰阳性（G^＋）球菌1873株（40．44％）。G^-杆菌对亚胺培南耐药率（3．27％-25．20％）最低，对氨苄西林耐药率（71.57％～92.11％）最高；G^＋球菌对万古霉紊耐药率（0）最低，对青霉素G耐药率（77．96％～100％）最高。结论临床感染菌不断增多，耐药现象日趋严重，耐药性监测对指导临床用药具有重要意义。Objective To investigate the distribution of clinical bacterial isolates and resistance to commonly used antimierobial agents. Methods The bacterial strains isolated from clinical samples in a hospital from 1998 to 2003 and the drug resistance were studied. Results Among the isolated 4 632 bacterial strains, gram-negative bacilli and gram- positive cocci were 2 759 （59.56%） and 1 873 （40.44%） respectively. The resistance of gram-negative bacilli to imipenem was the lowest （3.27% -25.20% ）, ampicillin was the highest （71.57% -92.11% ）. The resistance of gram-positive cocci to vancomyein was the lowest （0）, penicillin was the highest （77.96% -100% ）. Conclusion The clinical bacterial isolates are more and more, and antimicrobial agents resistance is serious. It is very important to select antimicrobial agents correctly according to the results of antimierobial susceptibility tests.

关 键 词：细菌 抗菌药物 抗药性 微生物 微生物敏感性试验 感染控制 

分 类 号：R969.3[医药卫生—药理学]