心力衰竭与Ca^（2＋）代谢异常及其药物影响  

HEART FAILURE AND ABNORMAL CALCIUM METABOLISM

作　　者：张雪娥[1] 王风芝[1] 巩书文[1] 

机构地区：[1]山西医学院第二附属医院心内科

出　　处：《中国新药杂志》1996年第2期129-131,共3页Chinese Journal of New Drugs

摘　　要：６２例心力衰竭患者血浆和红细胞内Ｃａ￣（２＋）测定结果显示，血浆Ｃａ￣（２＋）正常，红细胞内ｃａ￣（２＋）随心衰加重而增高，且以扩张性心肌病增高为著，其次是冠心病和风心病，高血压性心脏病未见异常。经治疗，随心衰好转红细胞内Ｃａ￣（２＋）下降，加用转换酶抑制剂、钙通道阻滞剂和β阻滞剂者下降显著。The Ca2+ content in plasma and intra-RBC in 62 patients with heart fail- ure were determined.It was discovered that the Ca2+ level in plasma are normal in all the patients but with higher intra-RBC Ca2+ concentration. The higher the intra-RBC Ca2+ con- tent the more serious the heari failure. This phenomenon is most obvious with dilated car- diomy opathy,then with coronary and rheumatic heart diseases,but not with hyperiensive heartd isease. The intra-RBc Ca2+ decreased significantly with t he improvement of the heart failure especially when treated with ACE inhibitor,calcium antagonist,or β-blocker.

关 键 词：心力衰竭 转换酶抑制剂 钙通道阻滞剂 Β阻滞剂 

分 类 号：R541.6[医药卫生—心血管疾病]