3种不同人参胶囊对果蝇寿命的影响  

Effects of three kinds of ginseng capsules on the life span of drosophila melanogaster's longevity

作　　者：白莉华[1] 厉曙光 王力强[1] 陈科[1] 

机构地区：[1]同济大学医学院,上海200092

出　　处：《上海预防医学》2006年第4期157-160,共4页Shanghai Journal of Preventive Medicine

基　　金：国家自然科学基金项目(30271123)

摘　　要：[目的]探讨不同人参胶囊延缓Oregon K野生型黑腹果蝇衰老的作用。[方法]收集8h内乳化未交配雌雄果蝇6000只，雌雄各半，随机分配在A、B、C3种人参胶囊的各自4个浓度组中，每个浓度组雌雄果蝇各200只，每4d更换1次培养基，每2d计数1次，用生存试验检测果蝇寿命。[结果]A胶囊0．06％、0．20％和0．60％浓度组的雌性果蝇与对照组比较延长平均寿命2．4～5．3d，延长雌蝇平均最高寿命为3．4～8．8d；B胶囊0．120％和0．360％浓度组雌蝇与对照组比较平均寿命延长2．5～3．6d，且延长平均最高寿命为2．4—3．4d；0．120％浓度组雄蝇与对照组比较延长平均最高寿命为2．8d；C胶囊0．24％和0．72％浓度组雌蝇与对照组比较延长平均寿命2．96—3．55d，0．24％浓度组雌蝇与对照组比较延长平均最高寿命3．45d；0．08％浓度组雄蝇与对照组比较延长平均寿命2．97d（P〈0．05或P〈0．01）。[ Objective] To investigate the impact of different kinds of processed ginseng capsules to the longevity test of Drosophila Melanogaster. [Methods] Newly trapped and not mated flies were collected within 8 hours, separated by sex and randomly put into different concentration of different （ A, B, C ） ginseng capsules. Each group containied 200 flies. There were 400 flies in one concentration group and there were 4 concentration groups for one kind of ginseng. The number of dead flies was counted every 2 days and the culture medium were replaced every 4 days until all flies died. [ Results ] The female＇s mean life-span（MSL） and maximum mean life - span（MMLS） of 0.06%, 0.20% and 0.60% concentration groups of A were longer than that of the control group, prolonged by 2.4 -5.3 days and 3.8-8.8days respectly. The female＇s MSL and MMSL of 0.12% and 0.36% groups of B were prolonged by 2.5 - 3.6 days and 2.4 -3.4 days respectivelyt male＇s MSL was prolonged by 2.8 days. The femaleg MSL of 0. 24% and 0. 72% groups of C were prolonged by 2.96 - 3.55 days, the female＇s MMSL of 0.24% group was prolonged by 3.45 days, male＇s MSL of 0.08% concentration group was prolonged by 2.97 days. And they were all significantly prolonged （ P 〈 0.05 or P 〈 0. 01 ）. [ Conclusion] Ginseng can prolong the longevity of Drosophila Melanogaster.

关 键 词：黑腹果蝇 人参 寿命 

分 类 号：R285.5[医药卫生—中药学]