原位心脏移植的临床研究  

Clinic Study of 3 Successful Orthotopic Heart Transplantations

作　　者：刘季春[1] 徐建军[2] 万于华[1] 饶华庚[1] 王勤[1] 李志平[1] 吴起才[1] 刘升[1] 刘晓明[1] 高涛[1] 陈干[1] 

机构地区：[1]南昌大学第一附属医院心胸外科,南昌330006 [2]南昌大学第二附属医院心胸外科,南昌330006

出　　处：《江西医学院学报》2006年第2期59-61,共3页Acta Academiae Medicinae Jiangxi

基　　金：江西省卫生厅重点招标资助项目(20020206)

摘　　要：目的报告3例原位心脏移植的临床研究经验。方法2001年8月-2003年12月为3例终末期心脏病患者施行原位心脏移植术，术式均采用双腔静脉吻合法，术后采用环孢素A、强的松及骁悉联合免疫抑制治疗。结果3例患者均顺利出院，心功能恢复至Ⅰ-Ⅱ级（NYHA），围术期无感染或严重排异反应发生。结论良好的心肌保护、完善的围术期处理以及合理的抗排异治疗是心脏移植手术成功的关键。Objective To report our experience of 3 successful orthotopic heart transplantations. Methods From Aug 2001 to Dec 2003, three patients with end-stage heart disease were underwent orthotopic heart transplantation. The technique of operations was orthotopic bicaval heart transplantation under extracorporeal circulation. Postoperative immunosuppressive therapy were applied with cyclosporine A plus prednisone and mycopenolatemofeti. Results Three patients were well recovered and discharged without acute rejection or infection and the heart function recovered to class Ⅰ -Ⅱ（NYHA）. Conclusion Excellent donor heart conservation, consummate management during the operative period and proper immunomppression treatment were key measures for successful heart transplantation.

关 键 词：心脏移植 免疫抑制 心肌保护 原位心脏移植 

分 类 号：R654.2[医药卫生—外科学]