Naegeli茶螺烷合成方法的改进  

Improvement on the Synthesis of Theaspirane

作　　者：孔宁川[1] 邱晔[2] 陈永宽[2] 

机构地区：[1]中科院昆明植物化学研究所,云南昆明650204 [2]云南烟草科学研究院,云南昆明650106

出　　处：《云南化工》2006年第2期12-14,共3页Yunnan Chemical Technology

基　　金：云南省科技厅高新园区专项基金;编号:2003GX12

摘　　要：对Naegeli报道的以β-紫罗兰酮为原料经乙酸异丙烯酯酯交换、硼氢化钠还原成逆紫罗兰醇再环化合成茶螺烷的方法进行了改进,改进后的合成方法反应副产物巨豆三烯含量从15%降至4%,反应时间明显缩短,茶螺烷的收率从75%提高至84.5%。Synthesis of theaspirane from β - ionone reported by Naegeli was improved. Content of megastigmatriene, a by - product was reduced from 15% to 4%, the reaction time was shortened obviously and the yield of theaspirane was enhanced from 75% to 84.5%.

关 键 词：茶螺烷 Β-紫罗兰酮 乙酸异丙烯醣 酯交换 环化 

分 类 号：TQ655[化学工程—精细化工]