左旋门冬氨酸鸟氨酸在急性重症胆管炎围手术期中的应用研究  

Clinical study of L-ornithine-Laspartate in treatment of Acute Cholangitis during the perioperative period

作　　者：林雨冬[1] 吴德柱[1] 王明元[1] 杜京丽[1] 王星[1] 

机构地区：[1]南京军区总医院95临床部,莆田351100

出　　处：《临床外科杂志》2006年第4期219-220,共2页Journal of Clinical Surgery

摘　　要：目的评估左旋门冬氨酸鸟氨酸在急性重症型胆管炎(ACST)患者围手术期的应用价值。方法将69例ACST患者随机分两组:A组为实验组(应用左旋门冬氨酸鸟氨酸组),共36例;B组为对照组(常规治疗组),共33例。术后第1、5、7天分别检测患者的白细胞计数、血小板计数、ALT、AST、TBIL以及监测肾功能BUN、Cr等指标。结果A组患者上述指标改善明显优于B组,两组数据差异有统计学意义(P<0.05)。结论ACST患者围手术期应用左旋门冬氨酸鸟氨酸可加快患者术后恢复,减少术后并发症及降低病死率。Objective To evaluate the value of L- ornithine- Laspartate in treatment of acute cholangitis of severe type （ACST） during perioperative period. Methods Sixty- nine cases of ACST were divided randomly into group A （ n = 36） receiving treatment with L-ornithine- Laspartate and group B （ n = 33） not receiving L - ornithine - Laspartate. Leucocytes, blood platelets, ALT, AST, TBIL, BUN and Cr were detected and analyzed on the first, third, and fifth day after operation. Results There were significant difference in indexes above between group A and group B（ P 〈 0.05 ）. Conclusion Treatment with L - ornithine - Laspartate in ACST during the perioperative period can increase the operative effect, decrease the complication and mortality.

关 键 词：左旋门冬氨酸鸟氨酸 急性重症型胆管炎 围手术期 治疗 

分 类 号：R657.4[医药卫生—外科学]