褶合曲线分析法同时测定泻痢停片中两组份的含量  

Simultaneous determineting contents of two constituents in Xieliting Tablets by convolution curve method

作　　者：赵玉佳[1] 高金波[1] 孟祥丽[1] 朱凤姝 

机构地区：[1]佳木斯大学化学与药学院,黑龙江佳木斯154007 [2]江苏正大天晴药业有限公司,江苏连云港150086

出　　处：《药学实践杂志》2006年第2期101-103,共3页Journal of Pharmaceutical Practice

摘　　要：目的:建立泻痢停的含量测定方法。方法:应用计算机辅助褶合曲线分析法结合计算机信息处理技术,不经分离直接测定磺胺甲(?)唑和甲氧苄氨嘧啶的含量。结果:磺胺甲(?)唑在0-20μg／mL范围内线性良好,回收率为99．85％,相对标准偏差为0．53％;甲氧苄氨嘧啶在0～12μg/mL范围内线性良好,回收率为 102．01％,相对标准偏差为3．14％。结论:该法简便、快速,结果可靠,重现性好。Objective： To establish a method for determination of contents in Xieliting tablets. Methods： The computer-aided conjuction curve method had been applied to determine sulfamethoxazol and trimethoprim. Results： The corresponding average recovery and the relative standard deviation of sulfamethoxazol and trimethoprim were 99. 85% ,0. 53%, 102.01% ,3. 14%, the linear range of suhamethoxazol and trimethoprim were 0 ～20μmL,0 ～12μg/mL. Conclusions： The method was satisfactory, simple and convenient and had a good accuracy.

关 键 词：褶合曲线分析法 泻痢停片 磺胺甲噁唑 甲氧苄氨嘧啶 

分 类 号：R917[医药卫生—药物分析学]