白藜芦醇衍生物及类似物的研究进展  

Advances in the Research of Resveratrol Derivatives and Analogues

作　　者：陈国良[1] 耿春梅[1] 刘湘永[1] 

机构地区：[1]沈阳药科大学制药工程学院,辽宁沈阳110016

出　　处：《药学进展》2006年第4期145-150,共6页Progress in Pharmaceutical Sciences

基　　金：国家自然科学基金青年基金资助项目(39800185);国家自然科学基金资助项目(30572248)

摘　　要：分类综述白藜芦醇衍生物和类似物的生理药理活性及其构效关系,其中包括羟基类似物及甲基化和酯类衍生物等。白藜芦醇衍生物和类似物与白藜芦醇一样具有多种生理药理活性,其中有些化合物的活性、选择性及稳定性均要强于白藜芦醇,故备受关注,成为近些年的研究热点。The biological and pharmaceutical activities and the structure-activity relationships of resveratrol derivatives and analogs which including hydroxyl, methyl, ester derivatives and so on were reviewed classifiedly. These compounds have so multiple biological and pharmacological activities as resveratrol, of which some are superior in activity, selectivity and stability to resveratrol and have become a focus of research in recent years.

关 键 词：白藜芦醇 衍生物 类似物 药理活性 构效关系 

分 类 号：O621.3[理学—有机化学]