胺碘酮联合培哚普利对初发性心房颤动复律后窦性心律维持的影响  

Conversion and Maintenance of Sinus Rhythm by Perindopril and Amiodaron in Recent Onset Atrial Fibrillation

作　　者：叶新和[1] 杨承建[1] 王晓兰[1] 徐欣[1] 郑义通[1] 马志伟[1] 

机构地区：[1]南京医科大学附属无锡市第二人民医院,214000

出　　处：《齐齐哈尔医学院学报》2006年第1期4-5,共2页Journal of Qiqihar Medical University

摘　　要：观察静脉注射胺碘酮对初发性心房颤动伴快心室反应的转复效果以及口服胺碘酮联合培哚普利对心房颤动转复后远期窦性心律的维持。将89例患者随即分为胺碘酮组(n=48例)和胺碘酮加培哚普利组(n=41例)。观察静注胺碘酮对房颤终止的效果。48小时内转复率70.8%。胺碘酮加培哚普利组对房颤复律后窦性心律的维持,左房内径缩小均明显优于胺碘酮组(P<0.05)。结论胺碘酮联合培哚普利对初发性房颤复律后窦性心律的维持优于胺碘酮组,对左房扩大的延缓及心功能改善均有一定作用。Objective To evaluate the efficacy and safety of intravenous amiodaron in recent onset atrial fibrillation with rapid vcntricular response in patients. To observe the maintenance ratios of sinus rhythm by pcrindopril and amiodaron. Methods Eighty- nine patients with atrial fibrillation were randomly divided into two groups （amiodaron group and amiodaron plus perindopril group）. Results The treatment lasted for 48 hours, the first intravenous anaiodaron for atrial fibrillation with rapid ventrieular response, the conversion ratios was 70.80%. Conclusions The maintcnance ratios of sinus rhythm and the left atrium remolding by maintenance of sinus rhythm and left atrium rcmolding by pcrindopril and amiodaron s better than by amiodaron.

关 键 词：胺碘酮 培哚普利 心房颤动 

分 类 号：R541.75[医药卫生—心血管疾病] R942.2[医药卫生—内科学]