机构地区:[1]河北医科大学第二医院核医学科,石家庄050000
出 处:《中华核医学杂志》2006年第2期77-80,共4页Chinese Journal of Nuclear Medicine
摘 要:目的应用平衡法核素心室显像(ERNA)与静息心肌灌注显像(MPI)判断冠状动脉解剖变异对急性下壁心肌梗死(AIMI)患者经皮冠状动脉介入治疗(PCI)后心室功能的影响。方法将47例经 PCI 的 AIMI 患者分为左优势型组(含均势型血液供应)12例和右优势型组35例。结合 ERNA和 MPI 结果,比较不同冠状动脉分布类型对 AIMI 患者 PCI 后双心室血流动力学和心肌供血,及3个月的短期预后影响。结果右、左优势冠状动脉供血类型患者出院前左室射血分数(LVEF)分别为(63.03±5.64)%和(57.67±7.35)%,P=0.012;高峰射血率(PER)为(3.52±0.66)和(2.93±0.73)舒张末期容积(EDV)/s,P=0.011;高峰充盈率(PFR)为(2.71±0.88)和(2.11±0.45)EDV/s,P=0.004;左心室游离壁局部射血分数(rEF)为(81.94±20.75)%和(67.25±16.54)%,P=0.032;右室射血分数(RVEF)为(37.89±3.86)%和(41.67±4.81)%,P=0.009;右心室游离壁 rEF 为(57.86±11.77)%和(67.83±10.38)%,P=0.012。PCI 后急性期左心室心肌血流灌注评分差异无显著性(P=0.357)。出院后3个月对比,仅 RVEF[(44.60±5.29)%和(48.00±3.30)%,P=0.043]差异有显著性。左心室心肌血流灌注评分差异无显著性(P=0.754)。2组自身配对研究显示各自均有多项功能参数改善。结论急性期,右优势型 AIMI 右心室功能损害更严重;恢复期,大部分患者右心室功能恢复,ERNA 可显示部分患者的持续右心室功能障碍。Objective To analyze the influence in anatomic variance of coronary .artery on function of left and right ventricles after acute inferior myocardial infarction (AIMI) treated with percutaneous coronary intervention therapy (PCI). Methods Forty-seven inferior AIMI patients were divided into 2 groups: 12 left dominant group [ including equipollent case,i, e. inferior wall of left ventricle supplied by left circumflex coronary artery ( LCX), right ventricle by right coronary artery (. RCA ) ] and 35 right dominant group (both inferior wall and right ventricle were supplied by RCA). Equilibrium radionuclide angiocardiography (ERNA) and myocardial perfusion imaging (MPI) were used for comparing the influence between different coronary artery flow patterns on biventricular hemodynamics, blood supply and prognosis of PCI after 3 months. Results Comparison of ventricular function in left and right dominant coronal artery type groups discharged 7 - 10 d after PCI, there were differences in left ventricular ejection fraction (LVEF) [ (63.03 ± 5.64 ) % vs (57.67 ± 7.35 ) %, P = 0. 012 ], peak ejection rate (PER) [ (3.52 =1: 0.66) end-diastolic volum (EDV)/s vs (2.93 ± 0.73 ) EDV/s, P = 0.011 ], peak filling rate (PFR) [ ( 2.71 ± 0. 88 ) EDV/s vs (2.11 ±0.45) EDV/s, P =0. 004], left free-wall regional ejection fraction [ (81.94 ±20.75)% vs ( 67. 25 ± 16.54 ) %, P = 0. 032 ], and right free-wall regional ejection fraction [ ( 57.86 ± 11.77 ) % vs (67.83 ± 10.38) %, P = 0. 012 ], right ventricular ejection fraction (RVEF) [ ( 37.89 ± 3.86) % vs (41.67 ±4.81)% ,P=0.09]. After 3 months,there was difference only in RVEF [ (44.60 ±5.29)% vs (48.00 ± 3.30 ) %, P = 0. 043 ], but no difference in myocardial perfusion of left ventricle ( P = 0. 357 ). Condusions In acute stage of AIMI right dominant group, there was more severe injury of right ventricle, in convalescent stage most of the right ventricular functi
关 键 词:心肌梗塞 冠状血管 支架 放射性核素心室显像术 心室功能
分 类 号:R542.22[医药卫生—心血管疾病]
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