慢性心力衰竭患者心率震荡检测及临床意义  

Detection and clinical significance of heart rate turbulence in patients with chronic heart failure

作　　者：王兴德[1] 李剑[1] 蒋兆华[1] 来依萍[1] 谷守明[1] 

机构地区：[1]上海市浦南医院心功能室,200125

出　　处：《临床心电学杂志》2006年第2期97-99,共3页Journal of Clinical Electrocardiology

摘　　要：目的观察慢性心力衰竭患者窦性心率震荡(HRT)现象的特征并探讨其临床意义。方法50例慢性心衰患者(心衰组)和30例非器质性心脏病患者(对照组)均接受24hHolter检查,分别计算HRT的初始值(TO)、震荡斜率(TS)及心率变异性的SDNN、SDANN、rMSSD值,并进行相关性分析。结果心衰组TO明显高于对照组(0.65±3.60%与-1.89±2.48%,P<0.01);心衰组TS明显低于对照组(2.96±1.23与10.24±4.47,P<0.001)。对照组TS与SDNN、SDANN、rMSSD的相关系数分别为-0.426、-0.385、-0.372(P均<0.05);心衰组TO与SDNN、SDANN、rMSSD的相关系数分别为0.489、0.465、0.436(P均<0.01),TS与SDNN、SDANN、rMSSD的相关系数分别为-0.745、-0.686、-0.597(P均<0.001)。结论慢性心衰患者中HRT现象明显减弱,TO与SDNN、SDANN、rMSSD值呈正相关,TS与SDNN、SDANN、rMSSD值呈负相关。Objective To explore the change of heart rate turbulence（HRT） in patients with chronic heart failure （CHF） and its clinical significance. Methods The HRT and HRV were measured in 50 patients with CHF and 30 patients without obvious heart disease （control group）. Turbulence onset（TO）, turbulence slope（TS） and SDNN,SDANN,rMSSD were measured by the original definitions using digitized Hoher recordings. Results The value of the TO was significantly higher in CHF group than in control group （0.65±3.60% vs -1.89±2.48%,P〈0.01）,The value of the TS was significantly lower in CHF group than in control group （2.96±1.23 vs 10.24±4.47,P〈0.001）;In CHF group, the correlation coefficient between TO and SDNN,SDANN,rMSSD was 0.489,0.465,0.436 respectively （P〈0.05,respectively）,the correlation coefficient between TS and SDNN,SDANN,rMSSD was -0.745,-0.686,-0.597 respectively （P〈0.0Ol,respectively）.Conclusions HRT was significantly blunted in CHF patients. There was positive correlation between TO and SDNN,SDANN,rMSSD and negative correlation between TO and SDNN, SDANN, rMSSD.

关 键 词：窦性心率震荡 心力衰竭 心率变异性 

分 类 号：R541.6[医药卫生—心血管疾病]