46例感染中毒症临床资料分析  

Clinical Analysis of 46 Cases With Septicemia

作　　者：曲亚丽[1] 龚五星[1] 蔡月明[2] 凌文辉[1] 

机构地区：[1]暨南大学医学院第三附属医院珠海市人民医院,珠海519000 [2]北京大学深圳医院

出　　处：《内科急危重症杂志》2006年第2期74-75,共2页Journal of Critical Care In Internal Medicine

摘　　要：目的分析46例感染中毒症患者血培养致病菌的种类、耐药谱、临床特征及预后。方法对我院住院诊断为感染中毒症的46例患者血培养和药敏结果及临床资料进行回顾性分析。结果46例感染中毒症患者血培养共分离出致病菌49株革兰阳性菌24株(49.0%),革兰阴性菌20株(40.8%),真菌5株(10.2%)。多种菌株对常用抗生素出现多重耐药。46例患者治愈33例(71.7%),死亡5例(10.9%),自动出院8例。结论随着新型抗生素在临床的广泛应用,革兰阳性菌感染中毒症有上升的趋势,并且呈多重耐药。Objective： To study the bacteria strain and resistance to commonly used antibiotics, clinical characteristics and prognosis of 46 patients with septicemia. Methods ： The results of blood cultures and drug sensitive test of 46 patients diagnosed as septicemia in our hospital were analysed retrospectively. Results： Fourty-nine strains of microorganisms were isolated from blood cultures of 46 septic patients including 24 strains（49. 0%） of gram positive bacteria, 20 strains （40. 8%） of gram negative bacteria and 5 straina（10. 2%） of fungus. Many strains developed multi-drug resistance to the commonly used antibiotics. Thirty-three （71.7%） of 46 eases were cured, 5（10. 9%） cases died and the other 8 cases gave up treatment at own risk. Conclusion.. With the clinical extensive use of new generation antibiotics, gram positive bacteria septicemia is increasing, and shows a trend of on multi-drug resistance.

关 键 词：感染中毒症 致病菌 耐药性 抗生素 

分 类 号：R515[医药卫生—内科学]