瘢痕疙瘩患者血清免疫球蛋白及补体变化观察  

The Observation of General Immunologic Factors in Patients with Keloids

作　　者：刘传君[1] 鲍卫汉[2] Liu Chuanjun, Bao Weihan （ 1. Affiliated Hospital of Medical School, Shaoxing University, Shaoxing, Zhejiang, 312000 ; 2. Peking University Third Hospital, Beijing, 100083）

机构地区：[1]绍兴文理学院医学院附属医院,浙江绍兴312000 [2]北京大学第三医院,北京100083

出　　处：《绍兴文理学院学报（自然科学版）》2006年第1期89-92,共4页Journal of Shaoxing College of Arts and Sciences

摘　　要：探讨免疫球蛋白及补体与瘢痕疙瘩发生的关系．方法：应用ARRAY360蛋白仪，比较34例诊断明确的瘢痕疙瘩患者和35例健康人的血清免疫球蛋白、补体的浓度．结果：瘢痕疙瘩患者血清IgG、IgE浓度升高，差异有显著性（P〈0．05），IgA、IgM、C3、C4水平两组无明显差异（P〉0．05）．结论：IgG、IgE及IgM与瘢痕疙瘩发生有关．Objective： In order to observe the relationship between general immunologic factors and keloid patients. Methods： A new equipment named ARRAY360 and made by Beckman was used to determine the serum levels of immunoglobulins, complements in 34 keloid patients and 35 normal controls. Results： The observation showed that serum IgG,IgE levels in patients with keloid were higher than that in control group serum（P 〈 0.05. IgA, IgM, C3 and C4 levels were not significantly different （P 〉 0.05）. Conclusion： The results suggest that some kinds of immunoglobulin may play an important role in the pathognesis of keloid, but we need to further observe whether they are the result or the cause of keloid.

关 键 词：瘢痕疙瘩(K) 免疫球蛋白(Ig) 补体(C) 

分 类 号：R619.6[医药卫生—临床医学;医药卫生—外科学]