卡介菌多糖核酸对复发性单纯疱疹患者外周血T淋巴细胞亚群的影响  

The Affection of BCG-Polysaccharide Nucleic Acid TOT- Lymphocyte subpopulation of the Patients with Recurrent Herpes Simplex

作　　者：王永贤[1] 王万卷[1] 田伟 

机构地区：[1]西安医科大学第二附属医院皮肤科

出　　处：《中国皮肤性病学杂志》1996年第3期142-143,共2页The Chinese Journal of Dermatovenereology

摘　　要：应用卡介菌多糖核酸治疗３２例复发性单纯疱疹患者，对治疗前、后Ｔ淋巴细胞亚群进行了检测。结果显示治疗前ＯＫＴ８细胞比正常人增多（Ｐ＜０．０２），ＯＫＴ４／ＯＫＴ８比值下降（Ｐ＜０．００２），治疗结束后ＯＫＴ４细胞比治疗前增多（Ｐ＜０．０２），ＯＫＴ４／Ｔ８比值升高（Ｐ＜０．００５）。提示复发性单纯疱疹患者细胞免疫功能已受核抑制，卡介菌多糖核酸具有较显著的免疫恢复和调节作用，对皮损复发有较好的控制。T-Lymphoeyte subpopulation of 32 patients with recurrent herpes simplex were detected before and after treatment with BCG-polysaccharide nucleic acid (BCG-PSN).The result showed that before treatment, OKT8 was higher than normal people (P<0.02),and the ratio of OKT4/OKT8 was lower (P<0.002).After treatment OKT4 increased (P<0.02 ),and the ratio of OKT4/OKT8 was higher (P<0.005 ).These indicated the cellular immune function of the patients was inhibited,and BCG-PSN could regulate the cellular immunity and could control the recurrent lesions significantly.

关 键 词：卡介菌多糖核糖 复发性 单纯疱疹 T淋巴细胞亚群 

分 类 号：R752.11[医药卫生—皮肤病学与性病学]