拉萨健康藏、汉族运动时肺泡──动脉血氧分压梯度的变化  

Changes in alveolar -arterial oxygen tension gradient during exercise in healthy Tibetans and Hans of Lhasa

作　　者：孙新甫 庄建国 黄肇荣[2] 

机构地区：[1]西藏自治区医学科学研究所 [2]美国科罗拉多大学医学院心肺研究室

出　　处：《西藏医药》1996年第3期8-11,共4页Tibetan Medicine

摘　　要：对海拔3658m的拉萨高原世居藏族10人及已习服的移居汉族9人的每分钟肺通气量（VE）、肺泡—动脉氧分压梯度（A－a）DO2及动脉血氧饱和度（SaO2）进行了测定，以了解西藏高原世居藏族的（A—a）DO2是否低于移居汉族，VE对其影响以及（A－a）DO2降低在维持SaO2上的作用。结果显示世居藏族在运动时VE较低，动脉血CO2分压（PaCO2）较高，（A－a）DO2明显低于移居汉族；在重度运动负荷时，世居藏族的PaO2及SaO2均高于汉族。结果提示（A－a）DO2的缩小代偿了VE。降低所致SaO2下降，对维持较高的SaO2、尤其在维持运动时的SaO2具有重要的作用。Ten Tibetan natives and nine acclima-tized Han immigrants of Lhasa (alti-tude3658m)were studied at rest and exercise to test whether the ventilation (VE ) and alveolararterial SaO2 gradient (A - aDO2 )were different between two groups which were responsible for maintaining better ar-terial SaO2. saturation. During exercise the Tibetans had lower V. and higher arterial CO2 tension and markedly decrease in (A -a)DO2 at all levels of exercise. The Tibetans decrease of (A - a ) DO2 compensated for their lower exercise VE that arterial PaO2 tension and SaO2 were higher than the value of acclimatized Han and better maintained during exercise, It suggests that the Ti-betans exhibited more efficient pulmonary gas exchange which compensated for re-duced VE and would be promotive of SaO2transportation at high altitude.

关 键 词：肺泡-动脉血氧分压梯度 肺通气 运动试验 高原低氧 

分 类 号：G804.2[文化科学—运动人体科学]