乳安颗粒质量控制的研究  

Study on quality control for ruan granule

作　　者：王光丽[1] 王爱娜[1] 秦雪梅[1] 张丽增[1] 郭小青[1] 

机构地区：[1]山西大学化学化工学院药学系,太原030006

出　　处：《药物分析杂志》2006年第3期348-351,共4页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:制定乳安颗粒质量控制方法。方法:采用薄层色谱法对处方中的柴胡、当归、浙贝母、连翘、白术、茯苓、延胡索进行定性鉴别;采用高效液相色谱法对处方中白芍中的芍药苷进行含量测定。结果:芍药苷在0.16～1.04μg范围内呈良好的线性关系(r=0.9998).加样回收率为98.9%～101.6%。结论:本方法能对乳安颗粒进行定性、定量检测,结果准确可靠。Objective To establish the method for quality control of Ruan Granule. Method： Radix Bupleuri, Radix Angelicae Sinensis, Bulbus Fritillariae Thunbergii, Fructus Forsythiae, Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Corydalis were identified by TLC, and the content of Paeoniflorin in white Peony root was determined by HPLC. Result： Paeoniflorin showed a good linear relationship at a range of 0.16 - 1.04 μg, r = 0.9998. The recovery was 98.9% - 101.6%. Conclusion： The methods are accurate and reliable.

关 键 词：乳安颗粒 定性鉴别 芍药苷 薄层色谱 高效液相色谱 

分 类 号：R917[医药卫生—药物分析学]