盐酸普罗帕酮片溶出度测定方法的研究  

Studies on dissolution of propafenone hydrochloride tablets

作　　者：常书阳 陈玉海 张小娟 倪天江 

机构地区：[1]焦作平光制药有限责任公司,河南焦作454003

出　　处：《药物分析杂志》2006年第3期404-405,共2页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立盐酸普罗帕酮片溶出度的测定方法。方法:以盐酸溶液(9→1000)为溶剂,转速50 r·min^(-1),检测波长210 nm。结果:浓度与吸收度呈良好线性,r=0.9999,低、中、高3种浓度的方法回收率在99.5%～100.1%。结论:该法简便、准确,可用于该片的质量控制。Objective： To establish a method of dissolution of propafenone hydrochloride tablets. Method： Regarding hydrochloric acid aqua （9→1000） as the solvent, the speed rate for 50 r·min^-1, Examination wave - length is 210 nm. Results： Thick degree and absorb the degree to report the good line, r =0.9999, The method recovery of low, mediun and high concentration were within 99.5% - 100.1%. Conclusion： The method is specific and accurate, and can be used for quatity control of the tropisetron mesylate tablets.

关 键 词：盐酸普罗帕酮片 溶出度 

分 类 号：R917[医药卫生—药物分析学]