筒鞘蛇菰镇痛有效部位的筛选  

Screening the Effective Fraction of Analgesin in Balanophora involucrata

作　　者：阮汉利[1] 李娟[1] 赵晓亚[1] 张勇慧[1] 皮慧芳[1] 吴继洲[1] 

机构地区：[1]华中科技大学同济医学院药学院,武汉430030

出　　处：《医药导报》2006年第5期383-384,共2页Herald of Medicine

基　　金：湖北省科技厅资助项目(基金编号:2004AA302B10)

摘　　要：目的筛选筒鞘蛇菰镇痛作用的有效部位。方法采用小鼠热板法和醋酸扭体法,筛选筒鞘蛇菰的镇痛有效部位。结果筒鞘蛇菰甲醇提取物的正丁醇部位能显著提高小鼠热刺激的痛阀;且对小鼠醋酸扭体反应具有显著的抑制作用。结论正丁醇部位为筒鞘蛇菰镇痛有效部位。Objective To screen the effective fraction of analgesia in Balanophora involucrata, Methods Hot plate and acetic acid writhing test in mice were used to evaluate the pain releasing effect of Balanophora involucrata, Results The n-BuOH fraction in methyl alcohol extract could significantly prolong the latencies of paw licking and decrease mice writhing. Conclusion The effective fraction of analgesia in Balanophora involucrata is n-BuOH.

关 键 词：筒鞘蛇菰 镇痛作用 有效部位 

分 类 号：R286[医药卫生—中药学] R965[医药卫生—中医学]