采用主动固定电极导线行右室流出道间隔部起搏的临床应用  

The feasibility and safety in patients with right ventricular sepal pacing

作　　者：汪芳[1] 张建军[1] 金炜[1] Jackson K Lieberman R 孙宝贵[1] 

机构地区：[1]上海市第一人民医院上海交通大学附属第一人民医院心内科,上海200080 [2]Department of Cardiac Electrophysiology,Haper University Hospital

出　　处：《中国心脏起搏与心电生理杂志》2006年第2期151-152,共2页Chinese Journal of Cardiac Pacing and Electrophysiology

摘　　要：目的 比较右室主动固定电极和被动电极导线应用结果，探索右室主动固定电极导线临床应用的可行性。方法 需要安置心脏起搏器患者59例，其中男20例、女39例；年龄在75．6±23．8（54-92）岁。患者为缓慢性心律失常或者严重心力衰竭。30例被动电极组，固定部位为右室心尖部；主动电极组29例，电极固定部位为右室流出道。结果 主动电极组与被动电极组即刻起搏参数比较没有明显的差异（起搏阈值：0．62±0．19V vs 0．78±0．09V，P〉0．05）。在出院后1，3，6个月随访起搏阈值与置入时比较也没有差异。只有1例出现主动电极从右室流出道间隔部脱位。主动电极置入时间和曝光时间较被动电极明显延长（45．03±1．99min vs 13．69±11．37min；17．88±7．23min vs 89．78±3．55min，P均〈0．05）。结论 使用主动固定电极进行右室流出道间隔部起搏是可行和安全的。Objective To investigate the feasibility and safety in patients with right ventricular sepal pacing with active fixation lead in the sepal pacing compared to passive fixation in right ventricular apex. Methods There were fifty-nine patients who were subdivided into two groups： group one（ Medtronic FIXS076, Medtronic FIX4093 active lead） and group two （Medtronic FIX4093 passive fixation lead）. The group one, the active lead was put in the right outflow tract. The patients were followed-up at 1,3,6 months after being discharged. Results Lead threshold did not show a significant difference between the two groups. The lead implantation time and fluoroscopy time in group one were longer than those in group two （45.03 ± 1.99 min vs 13.69 ± 11.37 min ; 17.88 ± 7.23 min vs 9.78 ± 3.55 min, all P 〈 0.05）. One patient from group one was found that the lead was extracted at 1-week post implantation because of lead displacement, Conclusions The sepal pacing with the active fixation lead is feasible and safe.

关 键 词：心血管病学 主动固定电极 被动固定电极 右室流出道起搏 安全性 

分 类 号：R318.11[医药卫生—生物医学工程]