双歧杆菌在严重烧伤大鼠肠黏膜损伤修复中的作用  

The role of bifidobacterial supplement on intestinal mucosal microstructural damage and reparation in rats after sever burns

作　　者：刘忠山[1] 刘宁[1] 李嘉琥[1] 李红卫[2] 

机构地区：[1]贵阳医学院附属医院整形烧伤科,贵州贵阳550004 [2]天津市第四医院烧伤科

出　　处：《中国医师杂志》2006年第4期463-464,共2页Journal of Chinese Physician

基　　金：贵州省卫生厅课题资助项目(G2003-19)

摘　　要：目的观察严重烧伤后补充外源性双歧杆菌对肠黏膜细微结构的影响。方法50只W istar大鼠随机分为烫伤并应用双歧杆菌组(A组),烫伤不应用双歧杆菌组(B组)和正常对照组(C组)。观察肠黏膜微观结构改变情况。结果A组较B组损伤轻,恢复快。结论双歧杆菌能减轻烫伤后肠黏膜细微结构损害,促进其修复。Objective To investigate the potential effect of bifidobacterial supplement on intestinal mucosal microstmctural damage and reparation in rats after sever bums. Methods Fifty wistar rats were randomly divided into bum control group （group B, n = 20）, bum plus treatment group （group A, n =20）, and control group （group C, n = 10）. The ileum mucosal injuries were observed under microscope. Results There were fewer ileum mucosal injuries and more reparation in group A compared with those of group B after thermal injury. Conclusion The supplement of exogenous bifidobacterium can reduce the ileum mucosal microstmctural injuries and facilitate the improvement of mucosal barrier function.

关 键 词：肠粘膜/治疗 烧伤 二裂菌属 

分 类 号：R644[医药卫生—外科学]