汗孔汗腺瘤的组织病理学与免疫组织化学研究  

Histopathological and immunohistochemical studies of poroid hidradenoma

作　　者：刘艳 

机构地区：[1]Department of Dermatology, Taipei Veterans General Hospital, National Yang-Ming University, 201, Shih-Pai Road, 112 Taipei, Taiwan

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第3期34-34,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Poroid hidradenoma (PH), a less common subtype of poroid neoplasm (PN) than eccrine poroma (EP), has not been immunohistochemically studied before. Six cases of PH (four solitary PH and two PH coexisted with other types of PN) were included in the study. Fifteen cases of EP were also included for comparison. Hematoxylin and eosin, Masson-Zimmerman silver stain, and a variety of immunohistochemical stains were used. Microscopically, PH is not connected to the epidermis. All six PH contained small poroid cells and larger, paler cuticular cells. Some PH showed separate or clusters of sebocytes (2/6), horn cysts (1/6), juxta-posed lymphoid follicles in the stroma (1/6) and foci of keratohyaline granules (2/6), none of which was seen in the 15 EP. Immunohistochemically, the keratin distribution of PH was very similar to that of EP. PH has a very small number of Langerhans cells (significantly lower than the overlying epidermis, P = 0.045), and a sparse deposition of melanin. We conclude that except the location, the histopathological and immunochemical differences between PH and EP were small. Sebaceous differentiation in two PH lesions suggested the possibility of an apocrine origin. The deeper parts of eccrine apparatus other than basaloid cells may have been more actively involved in the histogenesis of PH.Poroid hidradenoma （PH）, a less common subtype of poroid neoplasm （PN） than eccrine poroma （EP）, has not been immunohistochemically studied before. Six cases of PH （four solitary PH and two PH coexisted with other types of PN） were included in the study. Fifteen cases of EP were also included for comparison. Hematoxylin and eosin, Masson-Zimmerman silver stain, and a variety of immunohistochemieal stains were used. Microscopically, PH is not connected to the epidermis. All six PH contained small poroid ceils and larger, paler cuticular ceils. Some PH showed separate or clusters of sebocytes （2/6）, horn cysts （1/6）, juxta-posed lymphoid follicles in the stroma （ 1/6） and foci of keratohyaline granules （2/6）, none of which was seen in the 15 EP. Im- munohistochemically, the keratin distribution of PH was very similar to that of EP.

关 键 词：免疫组织化学研究 小汗腺汗孔瘤 汗腺瘤 组织病理学 苏木素-伊红 免疫组化染色 显微镜下观察 表皮细胞 PH 脂细胞 

分 类 号：R654.2[医药卫生—外科学] R739.5[医药卫生—临床医学]