沸石粉尘致肺纤维化作用实验研究  

Experimental Study on the Fibrotic Effect of Zeolite Dusts in Lungs

作　　者：宁滨莲 付军 刘锡成 常英华 涂建华 孙明山[1] 张忠义[1] 胡敏艳 李瑛[1] 高勇军 

机构地区：[1]黑龙江省劳动卫生职业病研究所,哈尔滨医科大学公卫学院,黑龙江省海林防疫站

出　　处：《中国工业医学杂志》1996年第3期141-143,共3页Chinese Journal of Industrial Medicine

摘　　要：本实验将５０ｍｇ和１００ｍｇ沸石粉尘分别进行大鼠气管内染尘。分别于染尘后３、６、１２、１８个月分批处死，进行肺脏及肺淋巴结的病理学形态观察及肺胶原含量测定。结果表明，沸石粉尘具有致肺纤维化作用，但较石英尘的致肺纤维化作用为弱。mg and 100 mg zeolite dusts were injected intracheally to 2 groups of wistar rats respectively.Parts of the animals were killed at 3.6.12 and 18 months later for pathomorphological examination and for the measurement of collagen in lungs and in their drainage lumph nodes. The results showed that the zeolite dusts did have fibrotic effects on lung tissues but it was weaker than the quartz group.

关 键 词：沸石粉尘 动物实验 肺纤维化 

分 类 号：R135.2[医药卫生—劳动卫生]