乙型肝炎病毒cccDNA研究进展  

Research advancement of hepatitis B virus covalently closed circular DNA

作　　者：张新枝 陈文郁 吴诗品 

机构地区：[1]暨南大学医学院第二附属医院(深圳市人民医院)感染内科,518020

出　　处：《国际消化病杂志》2006年第2期116-118,共3页International Journal of Digestive Diseases

摘　　要：国内外对HBVcccDNA的研究有了新进展。大量动物实验表明cccDNA的合成与体内的细胞因子及包膜蛋白之间有一定的相关性。随着PCR技术的进一步发展,新的检测方法逐渐形成并广泛应用于临床,能够对cccDNA进行具体量化,并且能够对临床抗病毒药物进行疗效的评估。The research to HBVeccDNA had made new advancement inside and outside. A great quantity animal experiments manifested that synthesize of cccDNA has a certainly correlation with cell factor and envelope protein in body. With the further advancement of PCR technology, new detect measures have formed gradually and applied in clinical popularly and are able to carry concrete quantification out ,moreover , they can appraise curative effects of clinical anti-virus medicines.

关 键 词：乙型肝炎病毒 CCCDNA 共价闭合环状DNA 

分 类 号：R373.21[医药卫生—病原生物学]