长沙地区住院分娩围生儿出生缺陷调查  

Birth defects among 6 037 births in Changsha,china

作　　者：夏爱斌[1] 蔡敏[1] 周锐[1] 

机构地区：[1]长沙市妇幼保健院妇产科,湖南410007

出　　处：《中国生育健康杂志》2006年第2期88-91,共4页Chinese Journal of Reproductive Health

摘　　要：目的探讨可能导致围生儿出生缺陷的各种相关因素。方法采用以医院为基础的监测方法收集资料。调查对象为孕28周至产后7 d在我院住院分娩的围生儿,包括活产、死胎和死产。结果共监测围生儿6 037例,检出出生缺陷儿110例,出生缺陷发生率为18．22‰,其中占前3位的依次为唇(腭)裂、先天性心脏病、先天性脑积水;出生缺陷儿中复合畸形的有13例,发生率为2．15‰(13／6 037);存在可能致畸因素者占66．36‰(73/110)。结论进一步开展婚前生育健康教育,避免致畸因素的危害,是减少出生缺陷发生的有力措施。Objective To investigate the various possible factors related to birth defects. Methods Data were collected through a hospital-based surveillance system. During the data collection period, all live or still births with 28 weeks or more of gestation were assessed within seven days after delivery. Results Among 6 037 births,110 defects were identified, with a prevalence rate of 18.22 ‰. The most common defects in order of prevalence were cleft lips with or without cleft palate, congenital heart defects, and congenital hydrocephalus. Thirteen cases were found to have more than one defects, account-ing for 2.13 ‰ of all births. Possible factors could be identified in 73 effected newborns, accounting 66.36 % of all cases. Conclusion Targeted education campaign is indiated in this population with the aim to avoid possible teratogenic factors exposure before conception.

关 键 词：围生儿 出生缺陷 相关因素 

分 类 号：R714.7[医药卫生—妇产科学]