Molecularly Imprinted Polymers with Bi-functional Monomers of Polymerizable Cyclodextrin Derivatives and 2-(Diethylamino)-ethyl Methacrylate for Recognition of Norfloxacin in Aqueous Media  

作　　者：Zhi Feng XU Lan LIU Qin Ying DENG 

机构地区：[1]School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275 [2]Department of Chemistry and Material Science, Hengyang Normal University, Hengyang 421008

出　　处：《Chinese Chemical Letters》2006年第5期641-644,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(No.20202015);the Doctoral Program Foundation of Institution of High Education of China(No.20020558026)for the financial support to the research.

摘　　要：A molecularly imprinted polymer was synthesized using 2-（diethylamino）ethylmethacry -late（DEM） and bismethacryloyl-β-cyclodextrin（BMA-β-CD） as bi-functional monomers and norfloxacin（NOF） as a template. The results of equilibrium binding experiments indicated that the polymer has affinity and specificity for NOF in aqueous media, and that its selective recognition ability for the template was higher than that of the imprinted polymers synthesized with a single functional monomer （BMA-β-CD or DEM）.A molecularly imprinted polymer was synthesized using 2-（diethylamino）ethylmethacry -late（DEM） and bismethacryloyl-β-cyclodextrin（BMA-β-CD） as bi-functional monomers and norfloxacin（NOF） as a template. The results of equilibrium binding experiments indicated that the polymer has affinity and specificity for NOF in aqueous media, and that its selective recognition ability for the template was higher than that of the imprinted polymers synthesized with a single functional monomer （BMA-β-CD or DEM）.

关 键 词：Molecular imprinting NORFLOXACIN Β-CYCLODEXTRIN binding specificity. 

分 类 号：R978[医药卫生—药品]