A Cooperative Approach for the Extraction of Protein Motifs  

A Cooperative Approach for the Extraction of Protein Motifs

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作  者:Chao CHEN Yuan Xin TIAN Xiao Yong ZOU Pei Xiang CAI Jin Yuan MO 

机构地区:[1]School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275

出  处:《Chinese Chemical Letters》2006年第5期707-710,共4页中国化学快报(英文版)

基  金:This work was supported by the National Natural Science Foundation of China (No.20475068, 20575082); the Natural Science Foundation of Guangdong Province (No.031577) ;the Scientific Technology Project of Guangdong Province (No.2005B30101003).

摘  要:By integrating the concept of cooperative approach, an extension of the fast annealing coevolutionary algorithm is presented in this paper. It outperformed the original algorithm in the domain of function optimization, especially in terms of convergence rate. It was also applied to a real optimization problem, protein motif extraction. And a satisfactory result has been obtained with the accuracy of prediction achieving 67.0%, which is in agreement with the result in the PROSITE database.

关 键 词:Cooperative approach global optimization protein motifs extraction. 

分 类 号:Q51[生物学—生物化学] Q503

 

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