肝静脉主干抗微波凝固的模拟实验  

The simulation of resistant capability of hepatic vein against microwave-coagulation

作　　者：张炽敏[1] 王剑翔[1] 张俊[1] 李嘉[1] 苏俊[1] 

机构地区：[1]东南大学附属中大医院超声科,江苏南京210009

出　　处：《中国医学影像技术》2006年第4期538-540,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨肝静脉主干旁肿瘤经皮微波凝固治疗的可行性。方法新鲜离体猪肝20只,10只制成模拟肝静脉循环模型,10只作为对照组,在超声引导下以60W/5min对肝静脉主干旁肝组织进行植入式微波凝固,分别观测、比较凝固区的大小、形态,观察肝静脉主干的受损状况。结果微波凝固后,声像图清晰显示实验组肝静脉,管径(5.46±0.19)mm,流速(31.68±1.95)cm/s,与凝固前无差异(P>0.05)。肉眼观,实验组的凝固区形态失去对称性,在微波天线与肝静脉之间的凝固范围随两者距离缩短而变小。肝静脉管壁无明显受损。结论肝静脉主干具有对抗微波凝固性能,肝静脉主干旁经皮微波凝固安全、可行。Objective To explore the possibility of percutaneous microwave coagulation therapy （PMCT） to liver tumor beside the root of hepatic vein （RHV）. Methods In 20 fresh pork livers in vitro, 10 were simulated with models of hepatic vein circulation, 10 were control sets. Guided by the ultrasound, the microwave electrodes were implanted to the liver tissue para-RHV, and the microwave emitted with 60 W/5 min. The size and shape of the coagulated area, and the impairment state of the RHV were measured respectively. The results were compared with the control groups. Results Post-microwave coagulation, the RHV of the models was clearly displayed sonographically, with an internal diameter of （5.46±0.19） mm, velocity of flow of （31.68±1.95） cm/s. There was no statistic difference comparing with pre-coagulation condition （P〉 0.05）. Under naked eyes, the coagulated shapes of the models were asymmetric. The coagulated area between microwave electrode and RHV was reduced when their distances shortened. There was no obvious impairment on the wall of RHV. Conclusion The RHV has resistibility against microwave coagulation. PMCT to the para-root of HV is safe and practical.

关 键 词：微波 肝静脉 凝固 模拟 实验 

分 类 号：R445.1[医药卫生—影像医学与核医学] Q95-33[医药卫生—诊断学]