利用酶促开环聚合和原子转移自由基聚合方法合成AB型嵌段共聚物  

Synthesis and Characterization of AB-Type Diblock Copolymer by Enzymatic Ring-opening Polymerization and ATRP

作　　者：沙柯[1] 李冬霜[1] 李亚鹏[1] 刘啸天[1] 艾鹏[1] 王薇[1] 王静媛[1] 

机构地区：[1]吉林大学化学学院麦克德尔米德实验室,长春130023

出　　处：《高等学校化学学报》2006年第5期985-987,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20574028)资助

摘　　要：Mono-hydroxyl terminated polycaprolactone(PCL) was prepared by Novozyme 435 catalyzed ring-opening polymerization(ROP) of ε-caprolactone(ε-CL) initiated by methanol,and subsequently converted to bromine ended PCL by the esterification of the resulting macromolecules with α-bromopropionyl bromide.The macroinitiators containing α-bromoester group were employed in the atom transfer radical polymerization(ATRP) of glycidyl methacrylate(GMA) with CuCl/2,2-bipyridine(bpy) as the catalyst system to obtain amphiphilic diblock copolymer PCL-b-PGMA.Mono-hydroxyl terminated polycaprolactone（PCL） was prepared by Novozyme 435 catalyzed ringopening polymerization（ROP） of 6-eaprolaetone（ε-CL） initiated by methanol, and subsequently converted to bromine ended PCL by the esterifieation of the resulting macromoleeules with α-bromopropionyl bromide. The maeroinitiators containing ,α-bromoester group were employed in the atom transfer radical polymerization （ ATRP） of glyeidyl methaerylate（GMA） with CUE1/2,2-bipyridine（bpy） as the catalyst system to obtain amphiphilie diblock eopolymer PCL-b-PGMA.

关 键 词：酶促开环聚合 原子转移自由基聚合(ATRP) 嵌段共聚物 固定化酶Novozyme 435 

分 类 号：O632[理学—高分子化学]