低分子肝素预防人工髋关节置换术后DVT的疗效及对血液流变学的影响  

The Effect of Low Molecule Heparin on Prevention of Deep veous thrombosis and Hemorheology after Artificial Hip Joint Replacement

作　　者：邱冰[1] 赵筑川[1] 田晓滨[1] 李波[1] 韩伟[1] 甄东[1] 

机构地区：[1]贵州省人民医院骨科,贵州贵阳550002

出　　处：《中国临床医学》2006年第2期288-289,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:了解人工髋关节王换术后低分子肝素防治深静脉血栓形成(DVT)的效果及对血液流变学的影响。方法:将 152例行人工髋关节置换术病人分为两组。80例术后给予低分子肝素,并观察血液流变学的变化,余72例不用低分子肝素。比较两组DVT发生率及血液流变学的变化。结果:术后用低分子肝素病人无一例发生DVT,血液流变学好于对照组;未用低分子肝素组有2例死亡,1例术后心跳、呼吸停止,42％术后肢体肿胀,9例彩超证实为DVT。所有用低分子肝素的病人未见有出血。结论:低分子肝素能明显改善人工关节置换术后病人的血液流变学,预防DVT,降低心脑血管并发症．是一种有效、安全、经济的方法。Objective：To find out the effect of prevention and cure on Deep veous thrombosis （DVT） and the influence to hemorheology by applied low-molecule heparin after artificial joint replacement. Methods： 152 cases of artificial joint replacement collected in 2000 from our hospital were divided into 2 groups , in which 80 were applied low--molecule heparin and the other 72 not. Incidence of DVT and change of hemorheology are studied between the two groups. Results： None happened DVT in the group applied low--molecule heparin and the data of hemorheology were superior compared with the control group. In the group not applied low--molecule heparin , there were 2 died, and one case happened heart failure and respiratory arrest. 42 % of the cases in the control group appeared limbs edema and 9 were confirmed DVT via color ultrasonic sound. None got hemorrhage in the group applied low--molecule heparin. Conclusion：Low-molecule heparin can apparently improve hemorheology of patients after artificial joint replacement , also it can prevent DVT and reduce vas complication of heart and brain , which is a effective ,safe and economical method.

关 键 词：低分子肝素 人工关节置换术 血液流变学 深静脉血栓 

分 类 号：R973.32[医药卫生—药品]