一种制备增产胺及其衍生物的新合成方法  

A NEW SYNTHETIC METHOD FOR THE PREPARATION OF 2-(3,4-DICHLOROPHENOXY)ETHYLDIETHYLAMINE AND ITS DERIVATIVES

作　　者：刘天麟[1] 刘晓展[1] 余盛良[1] 倪赤友[1] 

机构地区：[1]南开大学元素有机化学研究所

出　　处：《南开大学学报（自然科学版）》1996年第2期57-61,共5页Acta Scientiarum Naturalium Universitatis Nankaiensis

基　　金：国家自然科学基金

摘　　要：本文报道一种制备增产胺及其衍生物的新方法．３，４－二氯苯酚与环氧乙烷在ＮａＯＨ／异丙醇溶液中开环得到２－（３，４－二氯苯氧基）乙醇２ａ，产率９８％．２ａ与苯磺氯反应生成相应的苯磺酸酯３ａ，产率９７％．后者与二乙胺进行胺化得到增产胺１ａ，产率８５％．使用相同的方法还制得７个衍生物１ｂ～１ｈ．A new way for the preparation of title compunds was reported. Refluxing3,4-dichlorophenol with ethylene oxide in NaOH/isopropanol gave 2-(3,4-dichlorophenoxy)ethanol 2a in yield of 98%. Reaction of 2a with benzenesulfonyl chloride afforded benzenesulfonate 3a in 97%. Finally, amination of the resultant 3a with diethyamine in NaOH/DMF obtained 2-(3,4-dichlorophenoxy)ethyldiethylamine 1a in 85% yield. Similarly,seven derivatives 1b￣1h were prepared.

关 键 词：增产胺 植物生长调节剂 合成 衍生物 

分 类 号：TQ452.1[化学工程—农药化工]