钝化芳环的硝化反应  

Nitration of deactivated aromatics

作　　者：潘向军[1] 陈剑君[1] 

机构地区：[1]浙江工业大学浙西分校,浙江衢州324000

出　　处：《农药》2006年第5期323-324,共2页Agrochemicals

基　　金：浙江省教育厅项目(NO.20031087);浙江省教育厅青年教师资助计划(2003)

摘　　要：研究了一系列含有不同钝化基团的芳环化合物的硝化方法,考察了三氟甲基苯、对苯二甲酸二甲酯和对苯二甲酸用混酸直接硝化,收率分别为82.6%、79.8%和92.8%。对影响反应的因素,如硫酸的浓度和用量、反应温度和不同钝化基团的影响等进行了分析。Research was conducted on nitration of a series of aromatics containing different deactivating groups. Trifluoromethylbenzene, dimethyl terephthalate, and terephthalic acid were nitrated using an HNO3-H2SO4 mixture with yields of 82.6, 79.8, and 92.8%, respectively. The effect on the reaction of various factors was determined, including sulfuric acid use rate and concentration, reaction temperature, and different deactivating groups.

关 键 词：钝化芳环 硝化反应 混酸 

分 类 号：TQ450.1[化学工程—农药化工]