大黄配方颗粒原料药筛选研究  

Study on the Selection of Crude Drugs of Rhubarb Dispensing Granule

作　　者：李敏[1] 刘渝[1] 李丽霞[1] 孙佩[1] 

机构地区：[1]成都中医药大学药学院,四川成都610075

出　　处：《中药材》2006年第4期381-383,共3页Journal of Chinese Medicinal Materials

基　　金：国家科技部863项目(编号为2001BA701A40-5)

摘　　要：目的:筛选大黄配方颗粒的原料药。方法:依照《中国药典》2005版一部大黄项下规定,对不同产地及品种的大黄的TLC、干燥失重、总灰分、酸不溶性灰分、浸出物、总蒽醌和大黄酸、大黄素、大黄酚的含量进行测定和比较。结果:甘孜州大黄GAP基地产掌叶大黄各种指标含量均较高,且产量大,质量稳定可控。结论:确定甘孜州大黄GAP基地产掌叶大黄为大黄配方颗粒的原料药,为进一步制定大黄配方颗粒的原料质量标准提供了依据。Objective： To research and choose the best crude drugs of Rhubarb dispensing granule. Methods： According to stand- ard method from the eighth edition of China pharmacopoeia, determined and compared the contents of TLC, water, total ash, acid insoluble ash, extractives, total anthraquinones, rhein, emodin and chrysophanol of Rhubarb in diffrent producing areas and species. Results： The Contents of Rheum palmatum from Rhubarb GAP base in Ganzhi state were higher than others and the drug yield was large. Conclusion： This species are chosen to be the crude drugs for Rhubarb dispensing granule. The preliminary study provides the scientific grounds for next study about establishment of quality criteria.

关 键 词：大黄 原料药筛选 配方颗粒 质量标准 

分 类 号：R284.2[医药卫生—中药学]