郑州市某民办学校学生HBsAg阳性率和抗-HBs水平分析  

Analysis on the positive rate of HBsAg and anti-HBs level among students of a voluntary school in Zhengzhou City

作　　者：苗秋丽[1] 臧改华[1] 司珩[1] 

机构地区：[1]河南省疾病预防控制中心,河南郑州450003

出　　处：《疾病监测》2006年第3期135-136,147,共3页Disease Surveillance

摘　　要：目的了解近年来乙肝疫苗普遍接种后,郑州市某民办学校学生的 HBsAg 阳性率和抗-HBs 水平状况。方法对2003～2004年郑州市民办某小哈佛双语学校465名5～15岁入学新生进行了血清免疫检测(HBsAg 和抗-HBs)。结果 HBsAg 阳性率为0．4%(2/465),较1992 年有大幅度下降,2003～2004年0～6岁年龄组未检出；抗-HBs 阳性率为58．5%(272/465),较 1992年河南省调查的抗-HBs 阳性水平有大幅度提高。结论抗-HBs 阳性率随年龄增大而降低,而 HBsAg 阳性率则随年龄增大而升高,提示加强接种疫苗的重要性。Objective This study aimed to understand the positive rate of HBsAg and anti-HBs level among students of a voluntary school in Zhengzhou City in recent years after widespread inoculation of hepatitis B vaccine （HBV）. Methods A seroimmunity test （HBsAg and anti-HBs） was conducted for 465 students aged 5 to 15 years, who were newly enrolled in a Voluntary Little Harvard Bilingual School in Zhengzhou City from 2003 to 2004. Results The positive rate of HBsAg was 0.4%（2/465）, which was greatly lower than that of 1992, and no positive case was found in the group aged 0 to 6 years from 2003 to 2004. The positive rate of anti-HBs was 58.5%（272/465）, which was significantly higher than that obtained from the investigation in Henan Province in 1992. Conclusion The positive rate of anti-HBs decreased with increase of age, while that of HBsAg increased with age, which showed the importance of strengthening vaccination.

关 键 词：乙肝疫苗 乙肝表面抗原 乙肝表面抗体 加强接种 

分 类 号：R186[医药卫生—流行病学] R446.6[医药卫生—公共卫生与预防医学]