老年人心脑疾病与抗Hp抗体关系的研究  

Relationship Between Cardio-Cerebral Diseases of the Aged People and Anti-Hp Antibodies

作　　者：熊正南[1] 张光辉[1] 刘久法 

机构地区：[1]怀化医学高等专科学校附属医院,湖南怀化418000 [2]解放军第二炮兵535医院

出　　处：《实用预防医学》2006年第2期264-265,共2页Practical Preventive Medicine

摘　　要：目的探讨幽门螺旋杆菌感染与老年人心脑疾病的关系。方法采用酶联免疫法检测82例老年人心脑疾病患者和42例健康人血清抗Hp抗体IgGI、gAI、gM的含量,并进行对照分析。结果心肌梗塞组与脑梗死组的抗Hp抗体IgGI、gAI、gM阳性率均分别达到80%、60%、20%以上,两组结果比较差异无显著性(P>0.05)。对照组抗Hp抗体IgGI、gAI、gM阳性率分别为44.6%、25.5%、12.8%,明显低于心肌梗塞组和脑梗死组。结论Hp感染可能与老年人心脑疾病的发病有关。Objective To explore the relationship between helicobacter pylori （Hp） infection and cardio - cerebral diseases of the aged people. Method By means of enzyme- linked immunosorbent assay （ELISA）, 82 cases of cardiocerebral diseases of the aged people were tested, and the content of serum anti Hp antibodies from 42 cases of agematched healthy subjects were served as control. Result The positive rates of IgG, IgA, and IgM of anti- Hp antibodies of the myocardial or cerebral infarction patients were over 80 %, 60 % and 20 % respectively, no significant difference existed between them （P〉0.05）. But the positive rates of IgG, IgA, and IgM of the control group were 44.6%, 25.5% and 12.8% respectively, and they were obviously lower. Conclusion Hp infection might be associated with cardio- cerebral diseases in aged population.

关 键 词：心肌梗塞 脑梗死 幽门螺旋杆菌 

分 类 号：R542.22[医药卫生—心血管疾病] R743.33[医药卫生—内科学]