Q开关紫翠宝石激光治疗4656例色素性皮肤病临床分析  

Clinical Efficacy of Q-Switched Alexandrite Laser for Pigmentary Skin Diseases in 4656 Patients

作　　者：王宏伟[1] 王家璧[1] 刘跃华[1] 左亚刚[1] 晋红中[1] 姜国调[1] 李红春[1] 马东来[1] 

机构地区：[1]中国医学科学院中国协和医科大学北京协和医院皮肤科,北京100730

出　　处：《中国医学科学院学报》2006年第2期202-205,i0004,共5页Acta Academiae Medicinae Sinicae

摘　　要：目的观察Q开关紫翠宝石激光治疗皮肤色素性疾病的临床疗效与不良反应。方法用Q开关紫翠宝石激光治疗4656例皮肤色素性疾病,包括太田痣、雀斑、咖啡斑、文身、雀斑样痣、脂溢性角化、颧部褐青色痣、伊藤痣、斑痣,对其疗效及不良反应等进行观察。结果太田痣治疗6次有效率达92·31%,痊愈率达55·39%,治疗9次时痊愈率达100%;雀斑4次治疗可达到80%的痊愈率;脂溢性角化4次治疗100%痊愈;颧部褐青色痣4次治疗100%痊愈;文身包括文眉、文眼线和外伤文身经过3次治疗有效率超过77·18%,痊愈率超过50%;咖啡斑4次有效率50·00%,痊愈率21·43%;斑痣4次有效率50·00%,痊愈率25·00%;雀斑样痣4次有效率35·29%;伊藤痣4次有效率达25·00%。结论Q开关紫翠宝石激光对太田痣、雀斑、文身、脂溢性角化、颧部褐青色痣治疗效果好,对伊藤痣、雀斑样痣、斑痣及咖啡斑有一定疗效。Objective To evaluate the clinical efficacy and safety of Q-switched Alexandrite laser in the treatment of pigmentary skin diseases （PSDs）. Methods Totally 4 656 patients with PSDs were treated with Q-switched Alexandrite laser. These PDSs included nevus of Ota, seborrheic keratosis, tattoo, naevus fus- co-caeruleus zygomaticus, cafe-au-lait-spots, lentigo, naevus of Ito, and spilus nacvus. The outcomes and adverse events after treatment were oberserved. Results The response rate was 92.31% and the cure rate was 55.39% for nevus of Ota after six times of treatment, and the cure rate was 100% after nine times of treatment. The response rate was 100% for freckles, seborrheic keratosis, and naevus fuscocaeruleus zygomaticus after four times of treatment. The response rate was more than 77. 18% and the cure rate was more than 50% for tattoos after three times of treatment, including amateur tattoo, artificial eyebrow, eyelid lines, and traumatic tattoo. However, after four times of treatment, the response rate and the cure rate were only 50. 00% and 21.43% for cafe-au-lait spots , and 50. 00% and 25.00% for spilus naevus, respectively. The response rate was 35.29% for lentigo and 25.00% for nacvus of Ito/spilus naevus after four times of treatment. Conclusion Q-switched Alexandrite laser is effective in the treatment of nevus of Ota, seborrheic keratosis, tattoo, and nacvus fusco-caeruleus zygomaticus, but has limited efficacy for cafe-au-lait-spots, lentigo, naevus of Ito, and spilus naevus.

关 键 词：Q开关紫翠宝石激光 色素性疾病 疗效 

分 类 号：R758[医药卫生—皮肤病学与性病学]