微波辐射下以1,3-二溴-5,5-二甲基乙内酰脲为溴代试剂合成3-溴黄酮  

Microwave-Assisted Synthesis of 3-Bromoflavone Using 1,3-Dibromo-5,5-dimethyl-imidazolidine-2,4-dione as Brominating Agent

作　　者：赵培亮[1] 吴琼友[1] 周中振[1] 杨光富 

机构地区：[1]华中师范大学化学学院农药与化学生物学教育部重点实验室,武汉430079

出　　处：《有机化学》2006年第5期694-697,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.20432010;20476036;20172017);教育部跨世纪优秀人才资助计划;教育部重点科技项目;湖北省优秀创新群体(No.2004ABC002)资助项目.

摘　　要：报道了在微波辐射下以1,3-二溴-5,5-二甲基乙内酰脲(DBDMH)为溴化试剂合成3-溴黄酮的新方法,系统考察了反应温度、时间及反应物配比对反应收率的影响.A new and efficient synthesis of 3-bromoflavone using 1,3-dibromo-5,5-dimethyl-imidazolidine-2,4-dione as brominating agent under microwave irradiation was reported. The effects of molar ratio of reactants, reaction temperature and reaction time on the yields of product were investigated. Compared to the traditional heating method, microwave assisted synthesis shortened the reaction time from several hours to 15 min and gave better yields of products.

关 键 词：1 3-二溴-5 5-二甲基乙内酰脲 3-溴黄酮 微波辐射 

分 类 号：TQ242[化学工程—有机化工]