血小板减少对妊娠结局的影响  

The effective of idiopathic thrombocytopenic purpura to the termination of pregnancy

作　　者：邢风玲[1] 贾小芳[1] 冯力民[1] 

机构地区：[1]首都医科大学附属北京天坛医院妇产科,北京100050

出　　处：《武警医学》2006年第4期268-270,共3页Medical Journal of the Chinese People's Armed Police Force

基　　金：首都医学发展科研基金资助项目(NO.2002-1002)

摘　　要：目的探讨妊娠合并血小板减少围生期处理方法.方法总结我院2002年1月1日～2004年12月31日产后出血发病率,分娩总数2513例,产后出血为55例,并与16例妊娠合并血小板减少患者中产后出血发病率比较,及对血小板计数＜20×10^9/L者于分娩前后的处理,治疗方法为,对血小板计数＜20×10^9/L者于分娩前后短期使用糖皮质激素及血小板制剂.结果我院同期产后出血发生率为2.18%,16例血小板减少患者产后出血4例,占产后出血总数7.27%,与同期正常产妇相比,P＜0.01,差异有统计学意义;新生儿血小板均正常,无1例发生颅内出血,与同期新生儿颅内出血数相比,经统计学处理,P＞0.05,两者之间差异无显著性意义.产后42d检查,患者及新生儿血小板均正常.结论妊娠期血小板严重减少（血小板＜50×10^9/L）可能增加产后出血几率,但阴道分娩未增加新生儿颅内出血的危险.To investigate pregnancy accompanied with idiopathicthrombocytopenic purpura therapeutic methods, and the effects on maternal and infant health during pregnancy.Methods The data of 16 cases with thrombocytopenia during pregnancy in Tiantan Hospital, Capital university of Medical Science from Jun. 2002 to Nov. 2004 were analysed retrospectively. Results Pregnancy accompanied with idiopathic thrombocytopenic purpura may delivery from vagian . The occurrence of postpartum hemorrhage was 4 case. No newborn occurred bleeding. Prednis was considered. If the platelet count was less than 20 × 10^9/L section is the suitable delivery modus. Conclusions The health care and therapy during the perinatal period should be to improve the maternal and neonatal survival rate. Plaetlet transfusion may be considered when platelet count is less than 30 × 10^9/L. Mother with ITP may not affect infant. Pregnancy thrombocytopenia may enhence the dangerous of bleedingdiathesis in the mother.

关 键 词：妊娠 血小板 产后出血 

分 类 号：R554.605[医药卫生—血液循环系统疾病] R714.21[医药卫生—内科学]