原子吸收光谱法测定脑血管病患者脑脊液中微量元素  

Determination of Trace Elements in Cerebrospinal Fluid(CSF) of Patients Suffering Cerebrovascular Disease by Atomic Absorption Spectrometry

作　　者：孙瑞霞[1] 苏永祥[2] 孙剑辉[1] 

机构地区：[1]河南师范大学化学与环境科学学院河南省环境污染控制重点实验室,河南新乡453007 [2]焦作大学生化与环境工程系,河南焦作454003

出　　处：《光谱学与光谱分析》2006年第4期720-722,共3页Spectroscopy and Spectral Analysis

摘　　要：采用原子吸收光谱法对脑梗塞脑出血患者和正常人脑脊液不经消化，直接测定了微量元素Zn，Cu，Fe，Cd含量。该方法的加标回收率为97．6%～104．8％，相对标准偏差（RSD）小于5%。患者脑脊液中Cu含量较正常人低，Zn，Fe，Cd的含量均比正常人明显升高。该测定结果为研究其微量元素含量与脑血管疾病的相关关系以及该疾病的诊断、治疗和预防提供了有用的数据。The contents of some trace elements such as zinc, copper, iron and cadmium in cerebrospinal fluid（CSF） of normal persons and the patients who suffered cerebral hemorrhage or infarction were determined directly by atomic absorption spectrometry. The method is simple and convenient with a recovery ratio by standard addition being 97.6% to 104.8%, and a relative standard deviation（RSD） is lower than 5%. The test showed that except for the content copper lower than normal, the patients suffering cerebrovascular disease have much higher contents of zinc, iron and cadmium. The result provides useful data for studying the relation between the contents of these trace elements and cerebrovascular disease, as well as diagnosing, treating and preventing this disease.

关 键 词：原子吸收光谱法 脑血管病 脑脊液 微量元素 

分 类 号：O657.3[理学—分析化学]