傅立时变换中红外光谱法用于非损伤性血糖测定的研究  

STUDY ON NONINVASIVE MEASUREMENT OF BLOOD GLUCOSE WITH FTIR MID-INFRARED FIBER OPTICS TECHNIQUE

作　　者：沈韬[1] 彭卿[1] 翁诗甫[1] 周孝思[1] 吴瑾光[1] 

机构地区：[1]北京医科大学第三医院,北京大学化学与分子工程学院

出　　处：《光谱学与光谱分析》1996年第3期39-42,共4页Spectroscopy and Spectral Analysis

基　　金：国家攀登计划基金;国家教委博士生点基金

摘　　要：本文首次使用中红外光纤对人体血糖进行了非损伤性测定，实验显示，人手指的中红外光谱１１２３ｃｍ－１谱带的相对强度与人的血糖浓度同步改变，表明葡萄糖特征谱带的相对强度确可作为人血糖值的一个数量指标。这给红外光纤在生物医学领域中的应用展示了光明的前景。It is the first report that a noninvasive determination of glucose concentration in human body was carried out using FT--mid--infrared fiber optics. The results showed that the relative intensity change of 1123cm-1 band in mid--infrared spectra of thumb was in accord with the variation of blood glucose concentration in the human body.It suggested that the relative intensity of characteristic band 1123cm--1 of glucose could be used as an index of blood glucose level in human body and to monitor the blood glucose concentration fluctuation.This method could be developed as a noninvasive and convenient measurement of blood glucose for clinic diagnosis.

关 键 词：FTIR 糖尿病 血糖 葡萄糖 红外光谱法 非损伤性 

分 类 号：R587.104[医药卫生—内分泌] O657.33[医药卫生—内科学]