Effects of Replenishing Qi,Promoting Blood Circulation and Resolving Phlegm on Vascular Endothelial Function and Blood Coagulation System in Senile Patients with Hyperlipemia  

作　　者：杨惠民 韩丽蓓 盛彤 何琼 梁晋普 段树民 

机构地区：[1]Dongzhimen Hospital Affiliated to Beijing University of Traditional Chinese Medicine,Beijing 100700,China

出　　处：《Journal of Traditional Chinese Medicine》2006年第2期120-124,共5页中医杂志（英文版）

摘　　要：Objective:To observe the curative effect of the method of replenishing qi,promoting blood circulation andresolving phlegm on senile hyperlipemia and its effects on vascular endothelial function and blood coagulationsystem. Method:96 patients with senile hyperlipemia were randomly divided into a treatment group and acontrol group. 56 patients in the treatment group orally took Danshen Jueming Granules (丹参决明颗粒)while 40 patients in the control group orally took Xuezhikang Capsules (血脂康胶囊). Observed were indexesof blood lipid,vascular endothelial function,blood coagulation system and safety. Results:After treatment,the treatment group was obviously superior to the control group (P<0.05) in reducing plasma total cholesterol(TC) and low density lipoprotein cholesterol (LDL-C) as well as in the ratio of thromboxane BE (TXB2) to6-keto-prostaglandin F_(1α) (6-keto-PGF_(1α)),D-dimer (D-D) and fibrinogen (FIB). Conclusion:Danshen JuemingGranules have the effect of regulating metabolism of blood lipid,and improving vascular endothelial functionand blood coagulation system in senile patients with hyperlipemia.Objective： To observe the curative effect of the method of replenishing qi, promoting blood circulation and resolving phlegm on senile hyperlipemia and its effects on vascular endothelial function and blood coagulation system. Method： 96 patients with senile hyperlipemia were randomly divided into a treatment group and a control group. 56 patients in the treatment group orally took Danshen Jueming Granules （丹参决明颗粒） while 40 patients in the control group orally took Xuezhikang Capsules （血脂康胶囊）. Observed were indexes of blood lipid, vascular endothelial function, blood coagulation system and safety. Results： After treatment, the treatment group was obviously superior to the control group （P〈0.05） in reducing plasma total cholesterol （TC） and low density lipoprotein cholesterol （LDL-C） as well as in the ratio of thromboxane B2 （TXBz） to 6-keto-prostaglandin Flα （6-keto-PGF1α）, D-dimer （D-D） and fibrinogen （FIB）. Conclusion： Danshen Jueming Granules have the effect of regulating metabolism of blood lipid, and improving vascular endothelial function and blood coagulation system in senile patients with hyperlipemia.

关 键 词：血液循环 血管内皮功能 血液凝固系统 老年 血脂 

分 类 号：R259[医药卫生—中西医结合]