左旋多巴激发试验在生长发育迟缓儿童中的临床价值  

Value of the L-dopa provocation test in children with growth retardation

作　　者：赵广碧[1] 储小宏[1] 贾丽[1] 丛安丽[1] 叶志恒[1] 

机构地区：[1]安徽医科大学第一附属医院内分泌实验室,安徽合肥230022

出　　处：《安徽医药》2006年第5期349-349,共1页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨左旋多巴激发试验在生长发育迟缓儿童中的临床价值。方法对生长发育迟缓儿童采用左旋多巴激发试验,生长激素测定采用化学发光法。结果(1)生长激素的峰值在左旋多巴激发后30和60 m in出现最多(P<0.01);(2)生长激素完全缺乏者占29.8%,部分缺乏占55.3%,而完全不缺乏者仅占14.9%。结论儿童生长发育迟缓大多数是由于生长激素缺乏或部分缺乏所致。左旋多巴激发试验可作为临床诊断侏儒症的方法之一。Aim To investigate the clinical value of the L-dopa provocation test in children with growth retardation. Methods The L-dopa provocation test was performed on 47 children with growth retardation, and their serum levels of growth hormone （ GH ） were detected with chemiluminescence. Results （ 1 ） GH reached the peak since provocated by the L-dopa at 30 min and 60 rain mostly（ P 〈 0.01 ）. （2） GH was totally deficient in 14 cases and partly in 26 cases, while normal in 7 cases. Conclusions Growth retardation in children is mostly attributed to the total or partial deficiency of GH. The L-dopa provocation test can be used as one of the methods to diagnose midgetism.

关 键 词：左旋多巴 生长激素激发试验 

分 类 号：R725.8[医药卫生—儿科]